@@ -12,17 +12,17 @@ datasets:
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enables prediction of drug response in acute myeloid leukemia. Cell Rep Med.
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2024;5(1):101359.
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doi : https://doi.org/10.1016/j.xcrm.2023.101359
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- bladderpdo :
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+ bladder :
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description : Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer
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Data includes transcriptomics, mutations, copy number, and drug response data.
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references :
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- citation : Suk Hyung Lee, Wenhuo Hu, Justin T. Matulay, Mark V. Silva,
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Tomasz B. Owczarek, Kwanghee Kim, Chee Wai Chua, LaMont J. Barlow,
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Cyriac Kandoth, Alanna B. Williams, Sarah K. Bergren, Eugene J. Pietzak,
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Christopher B. Anderson, Mitchell C. Benson, Jonathan A. Coleman, Barry S. Taylor,
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- Cory Abate‑ Shen, James M. McKiernan, Hikmat Al‑ Ahmadie, David B. Solit, Michael M. Shen.
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- Tumor Evolution and Drug Response in Patient‑ Derived Organoid Models of Bladder Cancer.
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- Cell. 2018;173(2):515‑ 528.e17.
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+ Cory Abate- Shen, James M. McKiernan, Hikmat Al- Ahmadie, David B. Solit, Michael M. Shen.
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+ Tumor Evolution and Drug Response in Patient- Derived Organoid Models of Bladder Cancer.
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+ Cell. 2018;173(2):515- 528.e17.
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doi : https://doi.org/10.1016/j.cell.2018.03.017
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ccle :
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description : Cancer Cell Line Encyclopedia (CCLE).
@@ -31,15 +31,6 @@ datasets:
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Encyclopedia enables predictive modelling of anticancer drug sensitivity Nature.
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2012;483(7391):603-607. Published 2012 Mar 28.
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doi : https://doi.org/10.1038/nature11003
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- cptac :
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- description : The Clinical Proteomic Tumor Analysis Consortium (CPTAC) project
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- is a collaborative network funded by the National Cancer Institute (NCI) focused
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- on improving our understanding of cancer biology through the integration of
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- transcriptomic, proteomic, and genomic data.
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- references :
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- - citation : Lindgren CM, Adams DW, Kimball B, et al. Simplified and Unified Access
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- to Cancer Proteogenomic Data. J Proteome Res. 2021;20(4):1902-1910.
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- doi : doi:10.1021/acs.jproteome.0c00919
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ctrpv2 :
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description : Cancer Therapeutics Response Portal version 2 (CTRPv2)
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references :
@@ -113,31 +104,29 @@ datasets:
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with high-grade transformation in MPNST. JCI Insight. 2021;6(6):e146351. Published
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2021 Mar 22.
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doi : https://doi.org/10.1172/jci.insight.146351
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- mpnstpdx :
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- description : Patient derived xenograft data for MPNST
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nci60 :
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description : National Cancer Institute 60
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references :
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- citation : Shoemaker RH. The NCI60 human tumour cell line anticancer drug screen.
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Nat Rev Cancer. 2006;6(10):813-823.
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doi : doi:10.1038/nrc1951
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- pancpdo :
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+ pancreatic :
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description : Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer
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Data includes transcriptomics, mutations, copy number, and drug response data.
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references :
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- citation : Hervé Tiriac, Pascal Belleau, Dannielle D. Engle, Dennis Plenker, Astrid Deschênes,
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- Tim D. D. Somerville, Fieke E. M. Froeling, Richard A. Burkhart, Robert E. Denroche, Gun‑ Ho Jang,
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+ Tim D. D. Somerville, Fieke E. M. Froeling, Richard A. Burkhart, Robert E. Denroche, Gun- Ho Jang,
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Koji Miyabayashi, C. Megan Young, Hardik Patel, Michelle Ma, Joseph F. LaComb, Randze L. D. Palmaira,
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Ammar A. Javed, Jasmine C. Huynh, Molly Johnson, Kanika Arora, Nicolas Robine, Minita Shah,
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Rashesh Sanghvi, Austin B. Goetz, Cinthya Y. Lowder, Laura Martello, Else Driehuis, Nicolas LeComte,
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- Gokce Askan, Christine A. Iacobuzio‑ Donahue, Hans Clevers, Laura D. Wood, Ralph H. Hruban, Elizabeth Thompson,
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+ Gokce Askan, Christine A. Iacobuzio- Donahue, Hans Clevers, Laura D. Wood, Ralph H. Hruban, Elizabeth Thompson,
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Andrew J. Aguirre, Brian M. Wolpin, Aaron Sasson, Joseph Kim, Maoxin Wu, Juan C. Bucobo, Peter Allen,
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Divyesh V. Sejpal, William Nealon, James D. Sullivan, Jordan M. Winter, Phyllis A. Gimotty, Jean L. Grem,
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Dominick J. DiMaio, Jonathan M. Buscaglia, Paul M. Grandgenett, Jonathan R. Brody, Michael A. Hollingsworth,
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- Grainne M. O’ Kane, Faiyaz Notta, Edward Kim, James M. Crawford, Craig Devoe, Allyson Ocean, Christopher L. Wolfgang,
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+ Grainne M. O' Kane, Faiyaz Notta, Edward Kim, James M. Crawford, Craig Devoe, Allyson Ocean, Christopher L. Wolfgang,
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Kenneth H. Yu, Ellen Li, Christopher R. Vakoc, Benjamin Hubert, Sandra E. Fischer, Julie M. Wilson, Richard Moffitt,
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Jennifer Knox, Alexander Krasnitz, Steven Gallinger, David A. Tuveson. Organoid Profiling Identifies Common
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- Responders to Chemotherapy in Pancreatic Cancer. Cancer Discov. 2018;8(9):1112‑ 1129.
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+ Responders to Chemotherapy in Pancreatic Cancer. Cancer Discov. 2018;8(9):1112- 1129.
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doi : https://doi.org/10.1158/2159-8290.CD-18-0349
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prism :
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description : Profiling Relative Inhibition Simultaneously in Mixtures
@@ -150,17 +139,57 @@ datasets:
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genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell
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lines. Nat Biotechnol. 2016;34(4):419-423.
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doi : doi:10.1038/nbt.3460
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- sarcpdo :
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+ sarcoma :
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description : The landscape of drug sensitivity and resistance in sarcoma
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Data includes transcriptomics, mutations, and drug response data.
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references :
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- - citation : Ahmad Al Shihabi, Peyton J. Tebon, Huyen T. L. Nguyen,
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- Jomjit Chantharasamee, Sara Sartini, Ardalan Davarifar, Alexandra Y. Jensen,
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- Miranda Diaz‑ Infante, Hannah Cox, Alfredo E. Gonzalez, Summer Norris, Jantzen Sperry,
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- Jonathan Nakashima, Nasrin Tavanaie, Helena Winata, Sorel T. Fitz‑ Gibbon,
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- Takafumi N. Yamaguchi, Jae H. Jeong, Sarah Dry, Arun S. Singh, Bartosz Chmielowski,
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- Joseph G. Crompton, Anusha K. Kalbasi, Fritz C. Eilber, Francis Hornicek,
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- Nicholas M. Bernthal, Scott D. Nelson, Paul C. Boutros, Noah C. Federman, Jane Yanagawa,
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- Alice Soragni. The landscape of drug sensitivity and resistance in sarcoma.
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- Cell Stem Cell. 2024;31(10):1524‑ 1542.e4.
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+ - citation : Ahmad Al Shihabi, Peyton J. Tebon, Huyen T. L. Nguyen,
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+ Jomjit Chantharasamee, Sara Sartini, Ardalan Davarifar, Alexandra Y. Jensen,
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+ Miranda Diaz- Infante, Hannah Cox, Alfredo E. Gonzalez, Summer Norris, Jantzen Sperry,
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+ Jonathan Nakashima, Nasrin Tavanaie, Helena Winata, Sorel T. Fitz- Gibbon,
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+ Takafumi N. Yamaguchi, Jae H. Jeong, Sarah Dry, Arun S. Singh, Bartosz Chmielowski,
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+ Joseph G. Crompton, Anusha K. Kalbasi, Fritz C. Eilber, Francis Hornicek,
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+ Nicholas M. Bernthal, Scott D. Nelson, Paul C. Boutros, Noah C. Federman, Jane Yanagawa,
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+ Alice Soragni. The landscape of drug sensitivity and resistance in sarcoma.
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+ Cell Stem Cell. 2024;31(10):1524- 1542.e4.
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doi : https://doi.org/10.1016/j.stem.2024.08.010
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+ colorectal :
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+ description : Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients
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+ references :
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+ - citation : Marc van de Wetering, Hayley E. Francies, Joshua M. Francis, Gergana Bounova,
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+ Francesco Iorio, Apollo Pronk, Winan van Houdt, Joost van Gorp, Amaro Taylor-Weiner,
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+ Lennart Kester, Anne McLaren-Douglas, Joyce Blokker, Sridevi Jaksani, Sina Bartfeld,
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+ Richard Volckman, Peter van Sluis, Vivian S.W. Li, Sara Seepo, Chandra Sekhar Pedamallu,
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+ Kristian Cibulskis, Scott L. Carter, Aaron McKenna, Michael S. Lawrence,
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+ Lee Lichtenstein, Chip Stewart, Jan Koster, Rogier Versteeg, Alexander van Oudenaarden,
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+ Julio Saez-Rodriguez, Robert G.J. Vries, Gad Getz, Lodewyk Wessels, Michael R. Stratton,
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+ Ultan McDermott, Matthew Meyerson, Mathew J. Garnett, Hans Clevers, Prospective Derivation
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+ of a Living Organoid Biobank of Colorectal Cancer Patients, Cell, Volume 161, Issue 4, 2015,
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+ Pages 933-945, ISSN 0092-8674
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+ doi : https://doi.org/10.1016/j.cell.2015.03.053
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+ liver :
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+ description : Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
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+ references :
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+ - citation : Ji S, Feng L, Fu Z, Wu G, Wu Y, Lin Y, Lu D, Song Y, Cui P, Yang Z, Sang C, Song G,
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+ Cai S, Li Y, Lin H, Zhang S, Wang X, Qiu S, Zhang X, Hua G, Li J, Zhou J, Dai Z, Wang X,
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+ Ding L, Wang P, Gao D, Zhang B, Rodriguez H, Fan J, Clevers H, Zhou H, Sun Y, Gao Q.
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+ Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology.
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+ doi : https://doi.org/10.1126/scitranslmed.adg3358
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+ novartis :
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+ description : High-throughput screening using patient-derived tumor xenografts to predict clinical trial
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+ drug response
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+ references :
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+ - citation : Hui Gao, Joshua M. Korn, Stéphane Ferretti, John E. Monahan, Youzhen Wang, Mallika Singh,
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+ Chao Zhang, Christian Schnell, Guizhi Yang, Yun Zhang, O. Alejandro Balbin, Stéphanie Barbe,
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+ Hongbo Cai, Fergal Casey, Susmita Chatterjee, Derek Y. Chiang, Shannon Chuai, Shawn M. Cogan,
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+ Scott D. Collins, Ernesta Dammassa, Nicolas Ebel, Millicent Embry, John Green, Audrey Kauffmann,
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+ Colleen Kowal, Rebecca J. Leary, Joseph Lehar, Ying Liang, Alice Loo, Edward Lorenzana,
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+ E. Robert McDonald III, Margaret E. McLaughlin, Jason Merkin, Ronald Meyer, Tara L. Naylor,
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+ Montesa Patawaran, Anupama Reddy, Claudia Röelli, David A. Ruddy, Fernando Salangsang,
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+ Francesca Santacroce, Angad P. Singh, Yan Tang, Walter Tinetto, Sonja Tobler, Roberto Velazquez,
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+ Kavitha Venkatesan, Fabian Von Arx, Hui Qin Wang, Zongyao Wang, Marion Wiesmann, Daniel Wyss,
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+ Fiona Xu, Hans Bitter, Peter Atadja, Emma Lees, Francesco Hofmann, En Li, Nicholas Keen,
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+ Robert Cozens, Michael Rugaard Jensen, Nancy K. Pryer, Juliet A. Williams, William R. Sellers,
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+ High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug
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+ response, Nature Medicine, Volume 21, 2015, Pages 1318–1325.
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+ doi : https://doi.org/10.1038/nm.3954
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