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Q: split chromosomes #696

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zhengluo-zz opened this issue Apr 4, 2025 · 1 comment
Open

Q: split chromosomes #696

zhengluo-zz opened this issue Apr 4, 2025 · 1 comment
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@zhengluo-zz
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When calling peaks, will there be differences between the results obtained from split chromosomes and merged chromosomes?
@taoliu
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taoliu commented Apr 11, 2025

The genome background will be different. If you want to split chromosomes, you need to have the 'effective genome size' for each chromosome as used for -g option in macs3 callpeak command.

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