diff --git a/docs/reference/config.md b/docs/reference/config.md
index ecd89b5d09..ac75bd2516 100644
--- a/docs/reference/config.md
+++ b/docs/reference/config.md
@@ -592,7 +592,30 @@ The following settings are available:
 : Add the specified flags to the volume mounts e.g. `mountFlags = 'ro,Z'`.
 
 `docker.registry`
-: The registry from where Docker images are pulled. It should be only used to specify a private registry server. It should NOT include the protocol prefix i.e. `http://`.
+: Specify a custom registry from which to pull Docker images. It should be only used to specify a private registry server. It should NOT include the protocol prefix i.e. `http://`.
+: The custom registry is only applied to container images that don't specify a registry. Use `docker.registryOverrides` to also override fully-qualified container images.
+
+`docker.registryOverrides`
+: :::{versionadded} 25.06.0-edge
+  :::
+: A list of registries to override when specifying a custom registry with `docker.registry`. For example:
+
+  ```groovy
+  docker.registryOverrides = [
+    'community.wave.seqera.io',
+    'quay.io'
+  ]
+  ```
+
+: Nextflow will use this list to modify fully-qualified container images to use the registry specified by `docker.registry`.
+
+: :::{tip}
+  Use `nextflow inspect` to obtain the list of all containers used by a pipeline, from which you can determine the set of registries that need to be overridden.
+  :::
+
+: :::{warning}
+  The pipeline will fail if a container image cannot be overridden when using this setting, in order to prevent Nextflow from pulling containers from outside the custom registry.
+  :::
 
 `docker.remove`
 : Clean-up the container after the execution (default: `true`). See the [Docker documentation](https://docs.docker.com/engine/reference/run/#clean-up---rm) for details.
diff --git a/modules/nextflow/src/main/groovy/nextflow/container/ContainerHandler.groovy b/modules/nextflow/src/main/groovy/nextflow/container/ContainerHandler.groovy
index 2dae5abbc5..00738931d7 100644
--- a/modules/nextflow/src/main/groovy/nextflow/container/ContainerHandler.groovy
+++ b/modules/nextflow/src/main/groovy/nextflow/container/ContainerHandler.groovy
@@ -157,17 +157,36 @@ class ContainerHandler {
         if( !imageName )
             return null
 
-        String reg = this.config?.registry
-        if( !reg )
+        final registry = normalizeRegistry(this.config?.registry as String)
+        final registryOverrides = (this.config?.registryOverrides as List<String>)?.collect((r) -> normalizeRegistry(r))
+        if( !registry )
             return imageName
 
-        if( isAbsoluteDockerName(imageName) )
+        // apply the registry only to relative container images
+        // when registry overrides are not specified
+        if( !isAbsoluteDockerName(imageName) )
+            return registry + imageName
+
+        if( !registryOverrides )
             return imageName
 
-        if( !reg.endsWith('/') )
-            reg += '/'
+        // when registry overrides are specified, apply the custom registry also
+        // to fully-qualified container images
+        final newImageName = overrideRegistry(imageName, registry, registryOverrides)
+        if( newImageName )
+            return newImageName
+
+        // otherwise, raise an error to prevent Nextflow from pulling container images
+        // from outside of the custom registry
+        throw new IllegalArgumentException("Registry for container image '$imageName' not found in overrides")
+    }
 
-        return reg + imageName
+    static String normalizeRegistry(String registry) {
+        if( !registry )
+            return null
+        return registry.endsWith('/')
+            ? registry
+            : registry + '/'
     }
 
     static boolean isAbsoluteDockerName(String image) {
@@ -179,6 +198,14 @@ class ContainerHandler {
         image.contains('.') || image.contains(':')
     }
 
+    static String overrideRegistry(String imageName, String toRegistry, List<String> registryOverrides) {
+        for( final fromRegistry : registryOverrides ) {
+            if( imageName.startsWith(fromRegistry) )
+                return toRegistry + imageName.substring(fromRegistry.length())
+        }
+        return null
+    }
+
     /**
      * Normalize Udocker image name adding `:latest`
      * when required
diff --git a/modules/nextflow/src/test/groovy/nextflow/container/ContainerHandlerTest.groovy b/modules/nextflow/src/test/groovy/nextflow/container/ContainerHandlerTest.groovy
index 658bc51e10..cebc23bd2a 100644
--- a/modules/nextflow/src/test/groovy/nextflow/container/ContainerHandlerTest.groovy
+++ b/modules/nextflow/src/test/groovy/nextflow/container/ContainerHandlerTest.groovy
@@ -64,6 +64,26 @@ class ContainerHandlerTest extends Specification {
 
     }
 
+    def 'should override absolute docker image name when enabled' () {
+
+        given:
+        def registry = 'd.reg'
+        def registryOverrides = [ 'registry:5000' ]
+        def handler = new ContainerHandler([registry: registry, registryOverrides: registryOverrides])
+
+        when:
+        def result = handler.normalizeDockerImageName('registry:5000/cbcrg/hello')
+        then:
+        result == 'd.reg/cbcrg/hello'
+
+        when:
+        handler.normalizeDockerImageName('registry:8000/cbcrg/hello')
+        then:
+        def e = thrown(IllegalArgumentException)
+        e.message == "Registry for container image 'registry:8000/cbcrg/hello' not found in overrides"
+
+    }
+
     def 'test normalize shifter image name' () {
 
         given: